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Chemical structure of CAS 1024033-43-9

Azd-4017

CAS No.1024033-43-9
MDL No.MFCD25976912
MFC22H33N3O3S
MW419.60
InChI KeyNCDZABJPWMBMIQ-INIZCTEOSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1024033-43-9
Product NameAzd-4017

Biological Targets

HSD11B1

Associated Conditions

type 2 diabetes mellitus·pseudotumor cerebri·pituitary-dependent Cushing's disease·ocular hypertension·obesity
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: discovery of 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid (AZD4017).

Journal of medicinal chemistry • Vol. 55, Issue 12 • 2012
PMID: 22691057DOI: 10.1021/jm300592r

Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Minerva endocrinologica • Vol. 32, Issue 3 • 2007
PMID: 17912154

Glucocorticoids and cardiovascular disease.

European journal of endocrinology • Vol. 157, Issue 5 • 2007
PMID: 17984234DOI: 10.1530/EJE-07-0455

The metabolic syndrome.

Lancet (London, England) • Vol. 365, Issue 9468
PMID: 15836891DOI: 10.1016/S0140-6736(05)66378-7

Documentation