Semaglutide

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Semaglutide, a glucagon like peptide-1 (GLP-1) receptor agonist, was initially used to treat type 2 diabetes, and has rapidly developed into a key drug to deal with obesity, liver disease and other widespread metabolic disorders.

Related Information

Purity:99%+

Registration:GMP/DMF

Standard:USP/BP/EP

Biological Profile

Biological Targets

GLP1R

Associated Conditions

asthma·alcohol dependence·overweight body mass index status·Parkinson disease·diabetic nephropathy·

Key Intermediates

12 Items

Name	CAS No.	MDL No.
Octa(OtBu)-Glu-OtBu	1188328-39-3	MFCD34566912
(S)-2-(3-(1-(tert-Butoxycarbonyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanamido)-2-methylpropanoic acid	2765344-17-8	-
Octa(OtBu)-Glu(AEEA-AEEA-OSu)-OtBu	1118767-15-9	MFCD32661370
Tbuo-ste-glu(aeea-aeea-OH)-otbu	1118767-16-0	MFCD34186911
(22S)-22-carboxy-1-((2,5-dioxo-1-pyrrolidinyl)oxy)-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontan-41-oic acid	1169630-40-3	MFCD32704903
(S)-2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-5-yl)propanamido)-2-methylpropanoic acid	1446013-07-5	-
2-(((2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoyl)amino)-2-methyl-propanoic acid Trifluoroacetic acid salt (1:1)	1446013-08-6	-
(23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid	1662688-20-1	MFCD34563738
Boc-His(Trt)-Aib-OH	2061897-68-3	MFCD32173661
Fmoc-Glu(OtBu)-Gly-OH	866044-63-5	MFCD30475796
(S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate	1188328-22-4	-
Boc-his(trt)-aib-glu(otbu)-gly-OH	1890228-73-5	MFCD34597380