Orforglipron
CandidateCAS: 2212020-52-3
Sample Stock:
Orforglipron is a small molecule (non-peptide) GLP-1 receptor agonist that helps control blood glucose and reduce appetite by mimicking the action of natural GLP-1. It stimulates insulin secretion, inhibits glucagon release, and slows down gastric emptying, primarily used for blood glucose management and long-term weight control (obesity/overweight) in type 2 diabetes.
Related Information
Purity:99%+
Registration:GMP/DMF
Biological Profile
Associated Conditions
obesity·Hyperglycemia·type 2 diabetes mellitus
Key Intermediates
8 Items| Structure | Name | CAS No. | Sample Stock | MDL No. | Details |
|---|---|---|---|---|---|
 | (S)-1-(4-fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo(4,3-c)pyridin-3-yl)-1,3-dihydro-2H-imidazol-2-one | 2212022-56-3 | - | ||
 | 5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid | 2212021-83-3 | MFCD35115174 | ||
 | Orforglipron Impurity 60 | 2212020-29-4 | - | ||
 | 5-Bromo-4-fluoro-1H-indazole | 1082041-85-7 | MFCD11007927 | ||
 | 5-Bromo-4-fluoro-1-methyl-1h-indazole | 1784678-61-0 | MFCD30475009 | ||
 | 1-((1S,2S)-1-Cyano-2-methylcyclopropyl)-5-((4S)-2,2-dimethyloxan-4-yl)-N-methyl-N-phenylindole-2-carboxamide | 2212021-81-1 | - | ||
![Ethyl (S)-3-[(1-Cyano-2-propyl)amino]propanoate structure](https://static.dempochem.com/structures-bw/6979d328064ab2ea8c4fe937.svg) | Ethyl (S)-3-[(1-Cyano-2-propyl)amino]propanoate | 2212021-57-1 | - | ||
 | Orforglipron Impurity 61 | 2212021-63-9 | - |